In 2008, the Department of Cognitive Neuroscience of the Faculty of Psychology and Neuroscience at Maastricht University (UM) formulated its aspiration to further expand its brain research activities. The new research institute was to be named Brains Unlimited. The department also expressed a desire to make its advanced research facilities available to different research groups and external parties. To realize these aspirations, the UM commissioned the building of a new office, laboratory and research facility for brain research. The UM selected Wiegerinck Architectuur Stedenbouw, in partnership with Arup BV, to design the new building. In the selection of the design team, the UM and the department involved chose ‘synergy and encounter’ to serve as guiding concepts. The efforts of Brains Unlimited have been geared to the convergence of teaching, basic research and business, in both a physical and a virtual sense. Today, the main building houses various neuroscience activities, the UM’s researchers and NeuroPartner, a facilitator for launching business activities in the field of brain research. This building thus combines functions linked to research and teaching, which require laboratories, classrooms, an auditorium and offices, while it also has reception spaces. The building at Oxfordlaan 55 is part of the so-called Medizinische Kleinstadt, an urban development plan from 1990 for Randwijck North by the O.M. Ungers/von Brandt firm. According to this plan, new buildings were developed in their mutual relationship and in close interaction with their surroundings. The UM buildings along the Universiteitssingel constitute a kind of city wall, as if protecting the medical district behind it.